Methods of measuring retention of radio-isotopes in the knee and extra-articular spread in vivo.
نویسنده
چکیده
The two radionuclides most commonly used for intra-articular therapy are '98Au and 90Y. Both emit #-radiation, which is absorbed within a small distance from the site ofemission in tissue. The decay of 198Au is also accompanied by y-radiation, which can be detected from outside the body using a scintillation detector. 90Y, however, has no y-emission, but its presence can be detected from outside the body because Bremsstrahlung is produced when the, radiation is absorbed in tissue. This radiation has a broad energy spectrum, with a peak at low energies. The intensity is much lower than that from the same radioactivity of 198Au, since only about 1 per cent. of the energy of the fl-radiation produces Bremsstrahlung when absorbed in tissue. However, since relatively large amounts of radioactivity (several mCi.) are usually administered, it is possible to detect this radiation and to measure the amount of radioactivity at a particular site in the body. External counting may be performed using stationary scintillation detectors, a profile scanner, a gamma camera, or an area scanner (in order of decreasing sensitivity). Quantitative rather than qualitative methods of using these instruments are more likely to prove useful in comparing different regimes of treatment, and are necessary to estimate radiation dose.
منابع مشابه
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ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 32 Suppl 6 شماره
صفحات -
تاریخ انتشار 1973